Phacoemulsification (PE) cataract surgery is the gold standard in ophthalmology, being effective in improving vision in more than 90.0% of patients.

Thus, the use of platelet-rich plasma (PRP) in regenerative medicine has been investigated for the treatment of alopecia.

Objective: We performed a concise systematic review of the main clinical findings of the use of platelet-rich plasma for the treatment of alopecia.

Methods: The systematic review rules of the PRISMA Platform were followed. The research was carried out from August to September 2022 in Scopus, PubMed, Science Direct, Scielo, and Google Scholar databases. Scientific articles from the last 5 years were selected. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument.

Results: PRP was effective in increasing the proliferative activity of hair follicle cells and in increasing capillary density. In androgenetic alopecia, the addition of PRP with microneedling increased effectiveness and shortened the time required for optimal results, as did the combined use of PRP and minoxidil.

Conclusion: According to the results of the main randomized controlled trials, platelet-rich plasma showed efficacy in increasing the proliferative activity of hair follicle cells and increasing capillary density.

https://mednext.zotarellifilhoscientificworks.com/index.php/mednext/article/view/224